Chuck: Game's not over until I say it is.
Blair: Then go play with yourself.

Nate: I know you're there, I can hear you breathing on the other side of the door.

Chuck:[opens door] Nathaniel!
Nate: Where's the girl?
Chuck: In my dreams. I was trying to get some shut eye. What's on your mind?
Nate: Just my mom.
Chuck: Sounds Freudian.

Chuck: Mysterious financial transactions. Warring parents. Welcome to the Upper East Side.

Dan: How are you always so right?
Serena: Its easy when you're always wrong.

Rufus: My son, the writer.
Alison: Published writer.
Jenny: Yeah, you got your dream girl and you're star of the New Yorker. Maybe you should just die now.
Dan: It's true. I may have peaked.

Dan: I don't read Gossip Girl. That's for chicks.

Blair: All that matters to someone like Jenny right now are the 4 Gs, Guys, Girlfriends and Gossip Girl.

Blair: I'm innocent. Well, except for a crime of passion. I did something stupid with someone and even worse than doing that stupid thing I did the same stupid thing with someone else and pretended I'd never done that stupid thing before. You look confused... should I walk you through it?

Blair: Okay, I have a problem. I have a big problem! It starts with a capital RX.
Nurse: What drugs have you been taking?
Blair: Caffeine, Nicotine, Cadimine, Disprine, LSD, Driazapam, Flurazepam. All the pams really, I don't discriminate.

Dan: Google revenge and you get BlairWaldorf.com.

Chuck: if I knew his name, I'd kill him.
Nate: Because you kill people now? What, you gonna hunt him down with your scarf?
Chuck: Don't mock the
scarf, Nathaniel. It's my signature.