A recent analysis suggested women with endometriosis have over twice the odds of facing migraines, underscoring a potential connection between the two conditions that may usually go undetected.
The research, presented at a meeting of the American Neurological Association in San Diego, analysed 35 studies involving over 13 million women.
Scientists discovered a major overlap between endometriosis and migraine, with patient interviews detecting cases more effectively than short-term medical records.
Endometriosis happens when tissue similar to the uterine lining grows outside the uterus.
The condition can cause inflammation, severe pelvic pain and fertility problems.
Lead author Dr. Yohannes Woubishet Woldeamanuel of Mayo Clinic stated, “There’s a visibility gap because migraine and endometriosis are treated by different specialists and recorded separately, making the overlap easy to miss.”
Scientists discovered that medical records missed up to 90% of women having both conditions, suggesting the connection may be overlooked in routine healthcare.
Study co-author Dr. Megan Wasson, also from Mayo Clinic Arizona, encouraged women experiencing migraines and endometriosis symptoms to discuss both with their doctors.
She said neurologists should ask patients about multiple menstrual cramps and pelvic pain, while gynaecologists should screen for migraine symptoms.
The result further suggested the increased possibility that both conditions share common pain-signalling pathways.
Scientists suggested drugs that inhibit calcitonin gene-related peptide (CGRP), a chemical involved in migraine-related pain signalling, could possibly assist in relieving endometriosis related pain.
However, further research is needed to establish whether these medications are effective for endometriosis and to comprehend the relationship between the disorders.
The findings were presented at a medical meeting and are considered preliminary until published in a peer-reviewed journal.
Researchers stated greater awareness and screening could assist healthcare professionals identify patients experiencing both conditions and improve their treatment.
