Researchers in the UK have found a new reason behind much of the damage asthma causes.
According to BBC, the team from King's College London conducted a detailed study to examine the process, using both mice and samples of human lung tissue.
The study reveals that during an asthma attack, cells lining the airways are squeezed to destruction due to the intense pressure.
The researchers suggested to Science journal that medications aimed at preventing this damage rather than just addressing its consequences could potentially disrupt the cycle of harm.
Individuals with asthma have airways that are sensitive to triggers like pollen, pets, and physical activity.
These triggers lead to inflammation or swelling, resulting in symptoms such as coughing, wheezing, and difficulty breathing.
Currently available medications or inhalers can alleviate this inflammation and maintain open airways.
However, repeated attacks can result in permanent scarring and constriction of the air passages.
When an attack happens, the muscles around the air passages begin to squeeze and narrow, which is called bronchoconstriction.
While speaking to BBC, Lead researcher Professor Jody Rosenblatt explained that bronchoconstriction, the tightening of muscles around the air passages during asthma attacks, damages the lining of the airways.
This damage leads to ongoing inflammation, impaired healing, and increased susceptibility to infections, all of which contribute to further asthma attacks, she further added.
Alternatively, the researchers are investigating a potential preventative treatment called gadolinium, which appears to help - at least in mice.
However, extensive research is required to determine its safety and effectiveness in humans, a process that could span several years.
